New Step by Step Map For cees dekker
New Step by Step Map For cees dekker
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[Laughs] ‘It had been undoubtedly a fantastic threat! At the time, I was well knowledgeable that it could go Completely wrong Which I could develop into a lot less productive, but I just ignored that. Curiosity has always been my strongest driving drive. And fortunately all of it worked out.’
Sculpting nano-electrodes that has a transmission electron beam for electrical and geometrical characterization of nanoparticles.
This yielded a breakthrough. Inside of only some months, we have been able to evaluate transport by way of an individual solitary-walled carbon nanotube. According to very low-temperature experiments by a brilliant PhD university student in my group, Sander Tans (now a valued colleague and professor at Delft College of Technologies by having an active exploration lab at AMOLF in Amsterdam), we showed that carbon nanotubes ended up genuine quantum wires with quite long (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic conduct.
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of an individual wire bridging two electrodes
What distinguishes biology from chemistry is the fact that these factors with each other make up a dwelling program. The trick of explained life, I feel, lies in the interactions, the interplay of those molecules. The large dilemma with regards to the origin of lifestyle remains to be unanswered. How did we at any time evolve from straightforward molecules into your incredibly advanced methods we see currently? We do not know. I want to operate on These types of large, open issues.’
Move-pushed rotary motors like windmills and drinking water wheels push purposeful procedures in human Modern society. Even though examples of these rotary motors also feature prominently in cell biology, their synthetic building with the nanoscale has remained hard. In this article we demonstrate flow-driven rotary motion of a self-organized DNA nanostructure which is docked onto a nanopore in a thin sound-condition membrane. An elastic DNA bundle self-assembles into a chiral conformation upon phoretic docking onto the sound-condition nanopore, and subsequently displays a sustained unidirectional rotary motion of up to 20 rev s−one.
2003, demonstrated the first biosensors made outside of a carbon nanotube; solved the framework and mechanism of DNA fix proteins; and discovery of a brand new technique for fabricating solid-point out nanopores for DNA translocation
Resolving the step dimension in condensin-driven DNA loop extrusion identifies ATP binding as the step-generating process
Instance (4) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is demonstrated in grey, the rim from the pore is highlighted in red, in addition to a 3D rendering with the movement in the DNA rod is displayed.
Cees Dekker is Distinguished College Professor at TU Delft. Experienced to be a physicist, he pioneered nanotechnology with lots of discoveries on carbon nanotubes in the nineteen nineties. Since 2000, he moved to one-molecule biophysics and nanobiology. His present-day investigate concentrates on (i) nanopores for protein sequencing; (ii) chromosome ceesdekker.net framework, specifically SMC motor protein; and (iii) creating a living synthetic mobile from lifeless molecules. Dekker is really an elected member of your KNAW and fellow to the APS as well as IOP.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij achieved enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent layout in 2005. (nl)